Royal Air Force Typhoon fighter aircraft have operated alongside France's air force in a combined operation targeting an underground arms cache in Syrian territory used by the Daesh militant organization, per a report from the UK Ministry of Defence.
The site, pinpointed through surveillance, was thought to be storing arms and explosives, the statement said, and was situated in hills just north of the historic site of Palmyra in the heart of Syria.
"Our aircraft employed Paveway IV guided bombs to hit a number of approach shafts leading to the facility... early reports suggest the strike was effective," the ministry announced.
There was no sign of any civilian casualties in the operation late on Saturday and each participating jet made a safe return, the MoD added.
The Typhoon fighters were backed up by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as the so-called Islamic State - enforced jihadist rule over large swathes of both Syria and Iraq until 2019.
"This strike demonstrates the UK's leading role, and resolve to operate in unison with our partners, to eliminate any resurgence of the terrorist group and their dangerous and violent ideologies in the region," the British Defence Secretary the minister said.
British military aircraft have conducted overwatch operations over Syrian airspace to "forestall any attempted comeback" of IS following its routing at the Baghuz confrontation in 2019, the MoD reported.
"I want to thank the personnel of British forces who took part in this mission for their expertise and their courage," he added. "They were part of a great many British troops on duty over the holidays. This operation, to take out dangerous terrorists who threaten our safety, shows how UK forces are always on standby, continuously, protecting the UK domestically and strong abroad."
In December, the US military conducted what it termed a "major assault" on Islamic State objectives in the country, after an assault resulted in the deaths of two US troops and a civilian interpreter in the Palmyra area.
The United Nations estimates Daesh still maintains between 5,000 and 7,000 combatants in both countries.